Telmisartan tert-butyl ester

Telmisartan tert-butyl ester - Names and Identifiers

Name	4'-[[1,4'-Dimethyl-2'-propyl(2,6'-bi-1H-benzimidazol)-1'-yl]-methyl]-1,1'-biphenyl-2-carboxylic acid 1,1-dimethylethyl ester
Synonyms	TelMisartan IMpurity C TelMisartan EP IMpurity C TelMisartan tert-Butyl Ester tert-butyl 4,-((1,7,-dimethyl-2,-propyl-1H,3,H-[2,5,-bibenzo[d]imidazol]-3,-yl)methyl)-[1,1,-biphenyl]-2-carboxylate 1,4'-DiMethyl-2'-propyl(2,6'-bi-1H-benziMidazol)-1'-yl -Methyl -1,1'-biphenyl-2-carboxylic acid 1,1-diMethylethyl ester 4'-1,4'-DIMETHYL-2'-PROPYL(2,6'-BI-1H-BENZIMIDAZOL)-1'-YL-METHYL-1,1'-BIPHENYL-2-CARBOXYLIC ACID 1,1-DIMETHYLETHYL ESTER 4'-[[1,4'-Dimethyl-2'-propyl(2,6'-bi-1H-benzimidazol)-1'-yl]-methyl]-1,1'-biphenyl-2-carboxylic acid 1,1-dimethylethyl ester 2-(4-{[4-Methyl-6-(1-methyl-1H-1,3-benzodiazol-2-yl)-2-propyl-1H-1,3-benzodiazol-1-yl] methyl}phenyl)benzoic acid t-butyl ester [1,1'-Biphenyl]-2-carboxylic acid, 4'-[(1,4'-diMethyl-2'- propyl[2,6'-bi-1H-benziMidazol]-1'-yl)Methyl]-,1,1- diMethylethyl ester
CAS	144702-26-1
EINECS	1533716-785-6

Telmisartan tert-butyl ester - Physico-chemical Properties

Molecular Formula	C37H38N4O2
Molar Mass	570.72
Density	1.16
Melting Point	>83°C (dec.)
Boling Point	780.4±70.0 °C(Predicted)
Solubility	Chloroform (Slightly), Methanol (Slightly)
Appearance	Solid
Color	White to Off-White
pKa	5.00±0.10(Predicted)
Storage Condition	Refrigerator

Telmisartan tert-butyl ester - Introduction

4 '-[[1,4'-Dimethyl-2 '-propyl(2,6'-bi-1H-benzimidazol)-1 '-yl]-methyl]-1,1'-biphenyl-2-carboxylic acid 1,1-dimethylethyl ester is an organic compound with the chemical formula C35H38N4O2. The following is a detailed description of its nature, use, preparation and safety information:

Nature:
-Appearance: 4 '-[[1,4'-Dimethyl-2 '-propyl(2,6'-bi-1H-benzimidazol)-1 '-yl]-methyl]-1,1'-biphenyl-2-carboxylic acid 1,1-dimenthylethyl ester is a white solid.
-Solubility: It is soluble in some common organic solvents, such as chloroform, dichloromethane and ether.
-Melting point: Its melting point is usually around 180-190°C.

Use:
- 4 '-[[1,4'-Dimethyl-2 '-propyl(2,6'-bi-1H-benzimidazol)-1 '-yl]-methyl]-1,1'-biphenyl-2-carboxylic acid 1, 1-dimenthylethyl ester is an intermediate compound used in drug development and production.
-It can be used as a precursor of anti-cancer drugs and participate in the synthesis of specific drugs.

Method:
-Preparation of 4 '-[[1,4'-Dimethyl-2 '-propyl(2,6'-bi-1H-benzimidazol)-1 '-yl]-methyl]-1, the method of 1'-biphenyl-2-carboxylic acid 1,1-dimethylethyl ester can be completed by organic synthesis chemical reaction. The specific synthetic procedures and conditions may vary depending on the specific needs of the study.

Safety Information:
-Due to the lack of specific toxicity data and safety assessment information, appropriate protective measures should be taken when using and handling this compound, such as wearing chemical protective gloves and glasses, and make sure to operate in a well-ventilated place.
-As with any chemical, strictly follow laboratory safety procedures to avoid contact with skin, eyes and inhalation of gases.
-In the event of accidental exposure or contact, flush with plenty of water and seek medical assistance if necessary.

This is for 4 '-[[1,4'-Dimethyl-2 '-propyl(2,6'-bi-1H-benzimidazol)-1 '-yl]-methyl]-1,1'-A brief introduction to the nature, use, preparation and safety information of biphenyl-2-carboxylic acid 1,1-dimenthylethyl ester. For more detailed information, please refer to the relevant chemical literature and data.

Last Update：2024-04-09 19:05:57